兔抗SMAD4多克隆抗体

Background:

This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE).

Applications:

ELISA, WB, IHC

Name of antibody:

SMAD4

Immunogen:

Fusion protein of human SMAD4

Full name:

SMAD family member 4

Synonyms：

JIP; DPC4; MADH4; MYHRS

SwissProt:

Q13485

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and human brain

IHC Recommend dilution:

25-100

WB Predicted band size:

60 kDa

WB Positive control:

293T cells

WB Recommended dilution:

200-1000