手机扫码访问本站
微信咨询
英文 名称: Anti-TNNI3 rabbit polyclonal antibody
别 名: CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF
储 存: 冷冻(-20℃)
抗 原: TNNI3
宿 主: Rabbit
相关类别: 一抗
反应种属: Human, Mouse, Rat
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Applications:
ELISA, WB, IHC
Name of antibody:
TNNI3
Immunogen:
Fusion protein of human TNNI3
Full name:
troponin I type 3 (cardiac)
Synonyms:
CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF
SwissProt:
P19429
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human thyroid cancer and human breast cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
24 kDa
WB Positive control:
Mouse heart tissue
WB Recommended dilution:
200-1000