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技术规格
Background:
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
Applications:
ELISA, IHC
Name of antibody:
SIRT4
Immunogen:
Synthetic peptide of human SIRT4
Full name:
sirtuin 4
Synonyms:
SIR2L4
SwissProt:
Q9Y6E7
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human liver cancer and Human lung cancer
IHC Recommend dilution:
25-100