兔抗PDCD10多克隆抗体

Background:

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Applications:

ELISA, WB, IHC

Name of antibody:

PDCD10

Immunogen:

Fusion protein of human PDCD10

Full name:

programmed cell death 10

Synonyms：

CCM3, TFAR15

SwissProt:

Q9BUL8

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human tonsil and human renal cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

25 kDa

WB Positive control:

Hela, Jurkat and 231 cells

WB Recommended dilution:

200-1000