兔抗TFE3多克隆抗体

Background:

Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

Applications:

WB

Name of antibody:

TFE3

Immunogen:

Synthetic peptide of human TFE3

Full name:

transcription factor binding to IGHM enhancer 3

Synonyms：

TFEA; RCCP2; RCCX1; bHLHe33

SwissProt:

P19532

WB Predicted band size:

62 kDa

WB Positive control:

293 cells

WB Recommended dilution:

500-1000