兔抗MMP1多克隆抗体

Background:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

MMP1

Immunogen:

Fusion protein of human MMP1

Full name:

matrix metallopeptidase 1 (interstitial collagenase)

Synonyms：

CLG; CLGN

SwissProt:

P03956

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer and human lung cancer

IHC Recommend dilution:

50-200