兔抗PDK1多克隆抗体

Background:

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

PDK1

Immunogen:

Synthetic peptide of human PDK1

Full name:

pyruvate dehydrogenase kinase 1

SwissProt:

Q15118

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human ovarian cancer

IHC Recommend dilution:

25-100