兔抗SEMA4C多克隆抗体

Background:

Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.

Applications:

ELISA, IHC

Name of antibody:

SEMA4C

Immunogen:

Fusion protein of human SEMA4C

Full name:

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C

Synonyms：

SEMAF; SEMAI; SEMACL1; M-SEMA-F

SwissProt:

Q9C0C4

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and human thyroid cancer

IHC Recommend dilution:

25-100