兔抗SCNN1A多克隆抗体

Background:

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Applications:

ELISA, IHC

Name of antibody:

SCNN1A

Immunogen:

Synthetic peptide of human SCNN1A

Full name:

sodium channel, non-voltage-gated 1 alpha subunit

Synonyms：

BESC2; ENaCa; SCNEA; SCNN1; ENaCalpha

SwissProt:

P37088

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human colon cancer

IHC Recommend dilution:

25-100