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英文名称 : Anti-PITX2 rabbit polyclonal antibody
别 名 : RS; RGS; ARP1; Brx1; IDG2; IGDS; IHG2; PTX2; RIEG; IGDS2; IRID2; Otlx2; RIEG1
相关类别 : 一抗
抗 原 : PITX2
储 存 : 冷冻(-20℃)
宿 主 : Rabbit
反应种属 : Human, Rat
标 记 物 : Unconjugate
克隆类型 : rabbit polyclonal
技术规格
Background: |
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
Applications: |
ELISA, WB |
Name of antibody: |
PITX2 |
Immunogen: |
Fusion protein of human PITX2 |
Full name: |
paired-like homeodomain 2 |
Synonyms: |
RS; RGS; ARP1; Brx1; IDG2; IGDS; IHG2; PTX2; RIEG; IGDS2; IRID2; Otlx2; RIEG1 |
SwissProt: |
Q99697 |
ELISA Recommended dilution: |
2000-5000 |
WB Predicted band size: |
35 kDa |
WB Positive control: |
HepG2 cells |
WB Recommended dilution: |
500-2000 |