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技术规格
Background:
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Applications:
ELISA, WB, IHC
Name of antibody:
RPS6KA1
Immunogen:
Fusion protein of human RPS6KA1
Full name:
ribosomal protein S6 kinase, 90kDa, polypeptide 1
Synonyms:
RSK; HU-1; RSK1; MAPKAPK1A
SwissProt:
Q15418
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human breast cancer and human lung cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
83 kDa
WB Positive control:
K562 cells
WB Recommended dilution:
500-2000