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技术规格
Background:
This gene encodes a member of the resistance to inhibitors of cholinesterase 3-like family which functions as a chaperone of specific 5-hydroxytryptamine type 3 receptor and nicotinic acetylcholine receptor subtypes. The encoded protein influences the folding and assembly of these receptor subunits in the endoplasmic reticulum and expression on the cell surface. This protein contains an N-terminal transmembrane domain, a proline-rich spacer, and a cytosolic C-terminal coiled-coil domain. Alternative splicing results in multiple transcript variants.
Applications:
ELISA, IHC
Name of antibody:
RIC3
Immunogen:
Fusion protein of human RIC3
Full name:
RIC3 acetylcholine receptor chaperone
Synonyms:
AYST720; PRO1385
SwissProt:
Q7Z5B4
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human tonsil and Human liver cancer
IHC Recommend dilution:
50-300