兔抗OAS2多克隆抗体

Background:

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Applications:

ELISA, WB, IHC

Name of antibody:

OAS2

Immunogen:

Fusion protein of human OAS2

Full name:

2'-5'-oligoadenylate synthetase 2

SwissProt:

P29728

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

82 kDa

WB Positive control:

A375, RAW264.7, MC3T3-E1 cell lysates

WB Recommended dilution:

200-1000