兔抗NOD1多克隆抗体

Background:

This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

Applications:

ELISA, IHC

Name of antibody:

NOD1

Immunogen:

Synthetic peptide of human NOD1

Full name:

nucleotide-binding oligomerization domain containing 1

Synonyms：

CARD4; NLRC1; CLR7.1

SwissProt:

Q9Y239

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human liver cancer and Human colon cancer

IHC Recommend dilution:

50-200