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技术规格
Background:
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
Applications:
ELISA, WB, IHC
Name of antibody:
S1PR3
Immunogen:
Synthetic peptide of human S1PR3
Full name:
Sphingosine-1-phosphate receptor 3
Synonyms:
EDG3; LPB3; S1P3; EDG-3
SwissProt:
Q99500
ELISA Recommended dilution:
2000-10000
IHC positive control:
Human cervical cancer and Human thyroid cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
42 kDa
WB Positive control:
Human fetal brain tissue
WB Recommended dilution:
1000-5000