兔抗RPS6KA1(Ab-573) 多克隆抗体

Background:

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Applications:

WB, IHC

Name of antibody:

RPS6KA1(Ab-573)

Immunogen:

Synthesized non-phosphopeptide derived from human p90 RSK around the phosphorylation site of threonine 573 (L-M-T(p)-P-C).

Full name:

ribosomal protein S6 kinase, 90kDa, polypeptide 1

Synonyms：

RSK; HU-1; RSK1; MAPKAPK1A

SwissProt:

Q15418

IHC positive control:

Human colon carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

83 kDa

WB Positive control:

NIH/3T3 cells treated with PMA (125ng/ml, 30mins) lysate

WB Recommended dilution:

500-3000