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技术规格
Background:
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Applications:
ELISA, IHC
Name of antibody:
TFB2M
Immunogen:
Fusion protein of human TFB2M
Full name:
transcription factor B2, mitochondrial
Synonyms:
Hkp1; mtTFB2
SwissProt:
Q9H5Q4
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human colorectal cancer
IHC Recommend dilution:
50-200