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Background:
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Applications:
ELISA, WB
Name of antibody:
THRA/THRB
Immunogen:
Synthetic peptide of human THRA/THRB
Full name:
thyroid hormone receptor, alpha/beta
Synonyms:
AR7; EAR7; ERBA; CHNG6; ERBA1; NR1A1; THRA1; THRA2; ERB-T-1; c-ERBA-1; GRTH; PRTH; THR1; ERBA2; NR1A2; THRB1; THRB2; C-ERBA-2; C-ERBA-BETA
SwissProt:
P10827/P10828
ELISA Recommended dilution:
5000-10000
WB Predicted band size:
55 kDa
WB Positive control:
Human fetal brain tissue lysate
WB Recommended dilution:
200-1000