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						Background:
					 
						Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
					 
						Applications:
					 
						WB, IHC
					 
						Name of antibody:
					 
						SMAD3 (Phospho-Ser425)
					 
						Immunogen:
					 
						Synthetic peptide of human SMAD3 (Phospho-Ser425)
					 
						Full name:
					 
						SMAD family member 3 (Phospho-Ser425)
					 
						Synonyms:
					 
						LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436
					 
						SwissProt:
					 
						P84022
					 
						IHC positive control:
					 
						Human breast carcinoma
					 
						IHC Recommend dilution:
					 
						50-100
					 
						WB Predicted band size:
					 
						48 kDa
					 
						WB Positive control:
					 
						Hela cells treated with EGF
					 
						WB Recommended dilution:
					 
						500-1000
					
		
			
				 
			
					 
				
					 
			
				 
			
					 
				
					 
			
				 
			
					 
				
					 
			
				 
			
					 
				
					 
			
				 
			
					 
				
					 
			
				 
			
					 
				
					 
			
				 
			
					 
				
					 
			
				 
			
					 
				
					 
			
				 
			
					 
				
					 
			
				 
			
					 
				
					 
			
				 
			
					 
				
					 
			
				 
		
	
					 
				
					 
			
	
	 
 
	
	