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Background:
This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Applications:
ELISA, WB, IHC
Name of antibody:
TPM2
Immunogen:
Synthetic peptide of human TPM2
Full name:
Tropomyosin 2 (beta)
Synonyms:
DA1; DA2B; NEM4; TMSB; AMCD1
SwissProt:
P07951
ELISA Recommended dilution:
2000-10000
IHC positive control:
Human liver cancer and Human breast cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
33 kDa
WB Positive control:
Human leiomyosarcoma and mouse testis tissue
WB Recommended dilution:
1000-5000