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Background:
Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol(GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of Thy-1 lead to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to some of the initial biochemical description and characterization of a vertebrate GPI anchor and also the first demonstration of tissue specific differential glycosylation.
Applications:
ELISA, IHC
Name of antibody:
THY1
Immunogen:
Synthetic peptide of human THY1
Full name:
Thy-1 cell surface antigen
Synonyms:
CD90
SwissProt:
P04216
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human ovarian cancer
IHC Recommend dilution:
25-100