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技术规格
Background:
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Applications:
ELISA, IHC
Name of antibody:
TNF
Immunogen:
Synthetic peptide of human TNF
Full name:
tumor necrosis factor
Synonyms:
DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha
SwissProt:
P01375
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human colorectal cancerHuman liver cancer
IHC Recommend dilution:
20-100