兔抗SOCS7多克隆抗体

Background:

The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.

Applications:

ELISA, IHC

Name of antibody:

SOCS7

Immunogen:

Synthetic peptide of human SOCS7

Full name:

suppressor of cytokine signaling 7

Synonyms：

NAP4; NCKAP4

SwissProt:

O14512

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human ovarian cancer

IHC Recommend dilution:

50-200