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技术规格
Background:
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).
Applications:
ELISA, IHC
Name of antibody:
SULF2
Immunogen:
Synthetic peptide of human SULF2
Full name:
sulfatase 2
Synonyms:
HSULF-2
SwissProt:
Q8IWU5
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human tonsil
IHC Recommend dilution:
20-100