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技术规格
Background:
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake.
Applications:
ELISA, WB, IHC
Name of antibody:
STARD5
Immunogen:
Synthetic peptide of human STARD5
Full name:
StAR-related lipid transfer (START) domain containing 5
SwissProt:
Q9NSY2
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human breast cancer
IHC Recommend dilution:
40-150
WB Predicted band size:
24 kDa
WB Positive control:
Human fetal brain tissue
WB Recommended dilution:
500-2000