手机扫码访问本站


微信咨询

兔抗MLST8多克隆抗体

品牌:纪宁生物

货号:JN684

规格: 100ul 200ul 25ul

联系方式:021-54721350

立即询价 说明书下载

产品详情


中文名称: 兔抗MLST8多克隆抗体


英文名称: Anti-MLST8 rabbit polyclonal antibody


别      名: MTOR associated protein, LST8 homolog; GBL; LST8; POP3; WAT1; GbetaL


相关类别: 一抗


储      存: 冷冻(-20℃)


宿      主: Rabbit


抗     原: MLST8


反应种属: Human, Mouse, Rat


标  记  物: Unconjugate


克隆类型: rabbit polyclonal


技术规格


Background:

Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation.

Applications:

ELISA, WB

Name of antibody:

MLST8

Immunogen:

Fusion protein of human MLST8

Full name:

MTOR associated protein, LST8 homolog

Synonyms:

GBL; LST8; POP3; WAT1; GbetaL

SwissProt:

Q9BVC4

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

36 kDa

WB Positive control:

Human liver tissue lysate

WB Recommended dilution:

500-2000



友情链接:
elisa试剂盒 elisa检测试剂盒 上海晶抗生物 elisakit 植物elisa试剂盒 CAS号数据库
Copyright © 2006-2023 上海研域商贸有限公司. All rights reserved. 版权所有 沪ICP备13030217号-3 网站地图