兔抗SIGMAR1多克隆抗体

Background:

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

Applications:

ELISA, WB, IHC

Name of antibody:

SIGMAR1

Immunogen:

Fusion protein of human SIGMAR1

Full name:

sigma non-opioid intracellular receptor 1

Synonyms:

SRBP; ALS16; OPRS1; SR-BP; SIG-1R; SR-BP1; sigma1R

SwissProt:

Q99720

IHC positive control:

Human gastric cancer and human liver cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

25 kDa

WB Positive control:

Mouse liver and brain tissue, 293T, A549, A431 and PC3 cells

WB Recommended dilution:

500-2000