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中文名称：EGR1抗原（重组蛋白）
英文名称： EGR1 Antigen (Recombinant Protein)
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 87-337 amino acids of human EGR1 |
技术规格
|
Full name: |
early growth response 1 |
|
Synonyms: |
TIS8, AT225, G0S30, NGFI-A, ZNF225, KROX-24, ZIF-268 |
|
Swissprot: |
P18146 |
|
Gene Accession: |
BC073983 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). |
