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中文名称：FASTK抗原（重组蛋白）
英文名称： FASTK Antigen (Recombinant Protein)
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from C terminal 300 amino acids of humanFASTK |
技术规格
|
Full name: |
fas-activated serine/threonine kinase |
|
Synonyms: |
FAST |
|
Swissprot: |
Q14296 |
|
Gene Accession: |
BC000377 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. |
