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中文名称： FUS 抗原（重组蛋白）
英文名称： FUS Antigen (Recombinant Protein)
别 名： FUS RNA binding protein; TLS; ALS6; ETM4; FUS1; POMP75; HNRNPP2
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to C terminal 77 amino acids of human FUS |
技术规格
|
Full name: |
FUS RNA binding protein |
|
Synonyms: |
TLS; ALS6; ETM4; FUS1; POMP75; HNRNPP2 |
|
Swissprot: |
P35637 |
|
Gene Accession: |
BC000402 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. |
