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中文名称：HDAC8抗原（重组蛋白）
英文名称： HDAC8 Antigen (Recombinant Protein)
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 14-324 amino acids of human HDAC8 |
技术规格
|
Full name: |
histone deacetylase 8 |
|
Synonyms: |
HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1 |
|
Swissprot: |
Q9BY41 |
|
Gene Accession: |
BC050433 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. |
