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技术规格
Background:
The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) By similarity.
Applications:
ELISA, WB, IHC
Name of antibody:
SLC22A6
Immunogen:
Synthetic peptide of human SLC22A6
Full name:
Solute carrier family 22 (organic anion transporter), member 6
Synonyms:
OAT1, PAHT, HOAT1, ROAT1
SwissProt:
Q4U2R8
ELISA Recommended dilution:
2000-10000
IHC positive control:
Human colon cancer and Human liver cancer
IHC Recommend dilution:
50-200
WB Predicted band size:
56 kDa
WB Positive control:
Human fetal kidney tissue
WB Recommended dilution:
500-2000