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技术规格
Background:
The protein encoded by this gene is part of the anion exchanger (AE) family and is expressed in the erythrocyte plasma membrane, where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions.
Applications:
ELISA, IHC
Name of antibody:
SLC4A1
Immunogen:
Synthetic peptide of human SLC4A1
Full name:
solute carrier family 4 (anion exchanger), member 1
Synonyms:
DI; FR; SW; WD; WR; AE1; WD1; BND3; EPB3; CD233; EMPB3; RTA1A
SwissProt:
P02730
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human thyroid cancer
IHC Recommend dilution:
15-50