兔抗NTRK1多克隆抗体

Background:

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Applications:

ELISA, IHC

Name of antibody:

NTRK1

Immunogen:

Synthetic peptide of human NTRK1

Full name:

neurotrophic tyrosine kinase, receptor, type 1

Synonyms：

MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA

SwissProt:

P04629

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer and Human lung cancer

IHC Recommend dilution:

25-100