兔抗PDX1多克隆抗体

Background:

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Applications:

ELISA, WB, IHC

Name of antibody:

PDX1

Immunogen:

Synthetic peptide of human PDX1

Full name:

pancreatic and duodenal homeobox 1

Synonyms：

GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1

SwissProt:

P52945

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and Human esophagus cancer

IHC Recommend dilution:

15-50

WB Predicted band size:

31 kDa

WB Positive control:

Hela and Jurkat cells

WB Recommended dilution:

500-2000