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技术规格
Background:
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.
Applications:
ELISA, IHC
Name of antibody:
SETDB1
Immunogen:
Fusion protein of human SETDB1
Full name:
SET domain bifurcated 1
Synonyms:
ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4
SwissProt:
Q15047
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human esophagus cancerHuman thyroid cancer
IHC Recommend dilution:
50-300