兔抗TCAP多克隆抗体

Background:

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

Applications:

ELISA, IHC

Name of antibody:

TCAP

Immunogen:

Fusion protein of human TCAP

Full name:

titin-cap

Synonyms:

TELE; CMD1N; CMH25; T-cap; LGMD2G; LGMDR7; telethonin

SwissProt:

O15273

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human thyroid cancer

IHC Recommend dilution:

50-200