兔抗NDUFB11多克隆抗体

Background:

Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11), also known as ESSS, Np15, Np17.3 (neuronal protein 17.3) or p17.3, is a hydrophobic transmembrane protein belonging to the Complex I NDUFB11 subunit family. Ubiquitously expressed, NDUFB11 localizes to the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. The cAMP-dependent phosphorylation of NDUFB11 is important for the regulation of Complex I activity.

Applications:

ELISA, WB, IHC

Name of antibody:

NDUFB11

Immunogen:

Full length fusion protein

Full name:

NADH:ubiquinone oxidoreductase subunit B11

Synonyms:

ESSS; Np15; P17.3; NP17.3; CI-ESSS; LSDMCA3

SwissProt:

Q9NX14

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and human prostate cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

17 kDa

WB Positive control:

Mouse brain tissue，Mouse liver tissue，231 cell，K562 cell，A431 cell lysates

WB Recommended dilution:

1000-5000