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Background: |
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
SDCBP |
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Immunogen: |
Full length fusion protein |
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Full name: |
syndecan binding protein (syntenin) |
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Synonyms: |
ST1; MDA9; SYCL; MDA-9; TACIP18 |
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SwissProt: |
O00560 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human prostate cancer and Human brain |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
32 kDa |
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WB Positive control: |
Human fetal brain tissue and hela cell |
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WB Recommended dilution: |
500-2000 |