兔抗SPATA17多克隆抗体

Background:

Spata17 gene, which called MSRG11, by digital differential display of ESTs found only in testis. The deduced 292-amino acid protein was considered to be a member of the family of calmodulin (CaM)-binding proteins because it contained 3 short CaM-binding motifs containing conserved ile and gln residues (IQ motif). Spata17 protein was most abundant in the cytoplasm of round spermatids and elongating spermatids within seminiferous tubules of the adult testis. Expression gradually decreased in the manipulated testis of animals that underwent experimental unilateral cryptorchidism. Transient transfection experiments with a Spata17 expression construct in cultured spermatogonia GC-1 cells indicated that Spata17 accelerated apoptosis in a dose-dependent manner.

Applications:

ELISA, WB, IHC

Name of antibody:

SPATA17

Immunogen:

Fusion protein of human SPATA17

Full name:

spermatogenesis associated 17

Synonyms：

IQCH, MSRG11, MSRG-11, RP11-144C20.1

SwissProt:

Q96L03

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human ovarian cancer and human cervical cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

43 kDa

WB Positive control:

Human liver cancer tissue

WB Recommended dilution:

200-1000