兔抗MSH5多克隆抗体

Background:

This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

MSH5

Immunogen:

Fusion protein of human MSH5

Full name:

mutS homolog 5

Synonyms：

G7; NG23; MUTSH5

SwissProt:

O43196

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer and human brain

IHC Recommend dilution:

50-200

WB Predicted band size:

93 kDa

WB Positive control:

Mouse bladder tissue

WB Recommended dilution:

200-1000