兔抗UBE4A多克隆抗体

Background:

This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Applications:

ELISA, IHC

Name of antibody:

UBE4A

Immunogen:

Fusion protein of human UBE4A

Full name:

ubiquitination factor E4A

Synonyms:

E4; UFD2; UBOX2

SwissProt:

Q14139

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and human breast cancer

IHC Recommend dilution:

25-100