兔抗UBE4B多克隆抗体

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

UBE4B

Immunogen:

Synthetic peptide of human UBE4B

Full name:

ubiquitination factor E4B

Synonyms:

E4; UFD2; HDNB1; UBOX3; UFD2A

SwissProt:

O95155

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100