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英文名称： NGF Antigen (Recombinant Protein)
别 名： NGFB; HSAN5; Beta-NGF
储 存：冷冻（-20℃）
相关类别： 抗原
概 述
|
Fusion protein corresponding to a region derived from 122-241 amino acids of human NGF |
技术规格
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Full name: |
nerve growth factor (beta polypeptide) |
|
Synonyms: |
NGFB; HSAN5; Beta-NGF |
|
Swissprot: |
P01138 |
|
Gene Accession: |
BC126148 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. |
