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英文名称: VASH1 Antigen (Recombinant Protein)
别 名: KIAA1036
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Full length fusion protein |
Full name: |
vasohibin 1 |
Synonyms: |
KIAA1036 |
Swissprot: |
Q7L8A9 |
Gene Accession: |
BC009031 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Vasohibin-1 is a protein that in humans is encoded by the VASH1 gene. Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. |