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英文名称: NRP1 Antigen (Recombinant Protein)
别 名: NP1, NRP, BDCA4, CD304, VEGF165R
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述
Fusion protein corresponding to a region derived from 310-609 amino acids of human NRP1 |
Full name: |
neuropilin 1 |
Synonyms: |
NP1, NRP, BDCA4, CD304, VEGF165R |
Swissprot: |
O14786 |
Gene Accession: |
BC007737 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. |