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英文名称：PAK2 Antigen (Recombinant Protein)
别 名：PAK65; PAKgamma
储 存：冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 249-499 amino acids of human PAK2 |
|
Full name: |
p21 protein (Cdc42/Rac)-activated kinase 2 |
|
Synonyms: |
PAK65; PAKgamma |
|
Swissprot: |
Q13177 |
|
Gene Accession: |
BC069613 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. |
