手机扫码访问本站
微信咨询
英文名称： AKR1C4 Antigen (Recombinant Protein)
别 名： aldo-keto reductase family 1, member C4; C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 1-323 amino acids of human AKR1C4 |
技术规格
|
Full name: |
aldo-keto reductase family 1, member C4 |
|
Synonyms: |
C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD |
|
Swissprot: |
P17516 |
|
Gene Accession: |
BC020744 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. |
