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英文名称: GCAT Antigen (Recombinant Protein)
别 名: glycine C-acetyltransferase; KBL
储 存: 冷冻(-20℃)
相关类别: 抗原
概述:
Fusion protein corresponding to a region derived from 220-419 amino acids of human GCAT |
Full name: |
glycine C-acetyltransferase |
Synonyms: |
KBL |
Swissprot: |
O75600 |
Gene Accession: |
BC014457 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14. |