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英文名称： GGA2 Antigen (Recombinant Protein)
别 名： golgi associated, gamma adaptin ear containing, ARF binding protein 2; VEAR
储 存： 冷冻（-20℃）
相关类别： 抗原
概述：
|
Fusion protein corresponding to a region derived from 414-613 amino acids of human GGA2 |
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Full name: |
golgi associated, gamma adaptin ear containing, ARF binding protein 2 |
|
Synonyms: |
VEAR |
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Swissprot: |
Q9UJY4 |
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Gene Accession: |
BC000284 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. |
